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Functional Neuro-Imaging and Post-Traumatic Olfactory Impairment
OBJECTIVE: To evaluate via a research literature survey the anterior neurological significance of decreased olfactory functioning following traumatic brain injuries. MATERIALS AND METHODS: A computer literature review was performed to locate all functional neuro-imaging studies on patients with post...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122553/ https://www.ncbi.nlm.nih.gov/pubmed/21716782 http://dx.doi.org/10.4103/0253-7176.78504 |
Sumario: | OBJECTIVE: To evaluate via a research literature survey the anterior neurological significance of decreased olfactory functioning following traumatic brain injuries. MATERIALS AND METHODS: A computer literature review was performed to locate all functional neuro-imaging studies on patients with post-traumatic anosmia and other olfactory deficits. RESULTS: A convergence of findings from nine functional neuro-imaging studies indicating evidence for reduced metabolic activity at rest or relative hypo-perfusion during olfactory activations. Hypo-activation of the prefrontal regions was apparent in all nine post-traumatic samples, with three samples yielding evidence of reduced activity in the temporal regions as well. CONCLUSIONS: The practical ramifications include the reasonable hypothesis that a total anosmic head trauma patient likely has frontal lobe involvement. |
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