Cargando…

CCAAT/Enhancer-binding Protein β Inhibits Proliferation in Monocytic Cells by Affecting the Retinoblastoma Protein/E2F/Cyclin E Pathway but Is Not Directly Required for Macrophage Morphology

Monocytic differentiation is orchestrated by complex networks that are not fully understood. This study further elucidates the involvement of transcription factor CCAAT/enhancer-binding protein β (C/EBPβ). Initially, we demonstrated a marked increase in nuclear C/EBPβ-liver-enriched activating prote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gutsch, Romina, Kandemir, Judith D., Pietsch, Daniel, Cappello, Christian, Meyer, Johann, Simanowski, Kathrin, Huber, René, Brand, Korbinian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123039/ https://www.ncbi.nlm.nih.gov/pubmed/21558273 http://dx.doi.org/10.1074/jbc.M110.152538

Ejemplares similares

C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation
por: Huber, René, et al.
Publicado: (2015)

Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
Publicado: (1996)

TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms
por: Huber, René, et al.
Publicado: (2017)

Role of the CCAAT-Binding Protein NFY in SCA17 Pathogenesis
por: Lee, Li-Ching, et al.
Publicado: (2012)

Centromere protein E as a novel biomarker and potential therapeutic target for retinoblastoma
por: Shi, Ke, et al.
Publicado: (2021)

MARCKS Is an Essential Regulator of Reactive Oxygen Species Production in the Monocytic Cell Type
por: Huber, René, et al.
Publicado: (2022)

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAF(V600E)-mutant melanoma
por: Harris, Antoneicka L., et al.
Publicado: (2017)

Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein
por: Munakata, Tsubasa, et al.
Publicado: (2007)

Regulation of Id2 expression by CCAAT/enhancer binding protein β
por: Karaya, Kazuhiro, et al.
Publicado: (2005)

CCAAT/enhancer binding proteins in normal mammary development and breast cancer
por: Zahnow, Cynthia A
Publicado: (2002)

Biological roles of CCAAT/Enhancer-binding protein delta during inflammation
por: Ko, Chiung-Yuan, et al.
Publicado: (2015)

CCAAT/Enhancer Binding Protein β Is Dispensable for Development of Lung Adenocarcinoma
por: Cai, Yi, et al.
Publicado: (2015)

Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer
por: Caldon, C Elizabeth, et al.
Publicado: (2010)

Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells
por: Rogers, Samuel, et al.
Publicado: (2015)

The Canine Papillomavirus and Gamma HPV E7 Proteins Use an Alternative Domain to Bind and Destabilize the Retinoblastoma Protein
por: Wang, Jingang, et al.
Publicado: (2010)

Putting Cyclin E in the trash
por: Leslie, Mitch
Publicado: (2013)

Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ
por: Yamaguchi, Junna, et al.
Publicado: (2015)

CCAAT/enhancer binding protein β is required for satellite cell self-renewal
por: Lala-Tabbert, Neena, et al.
Publicado: (2016)

The CCAAT/Enhancer-Binding Protein Family: Its Roles in MDSC Expansion and Function
por: Wang, Wenxin, et al.
Publicado: (2019)

CCAAT/Enhancer-Binding Proteins in Fibrosis: Complex Roles Beyond Conventional Understanding
por: Wang, Lexun, et al.
Publicado: (2022)

CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury
por: Cao, Yan, et al.
Publicado: (2021)

Spliceosomal protein E regulates neoplastic cell growth by modulating expression of Cyclin E/CDK2 and G2/M checkpoint proteins
por: Li, Z, et al.
Publicado: (2008)

Quantum dot assisted tracking of the intracellular protein Cyclin E in Xenopus laevis embryos
por: Brandt, Yekaterina I, et al.
Publicado: (2015)

Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells
por: Rotgers, E, et al.
Publicado: (2014)

Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice
por: Okamoto, Ryoko, et al.
Publicado: (2014)

CCAAT/Enhancer Binding Protein β in relation to ER Stress, Inflammation, and Metabolic Disturbances
por: van der Krieken, Sophie E., et al.
Publicado: (2015)

Detrimental role for CCAAT/enhancer binding protein δ in blood-borne brain infection
por: Duitman, JanWillem, et al.
Publicado: (2016)

CCAAT/Enhancer Binding Protein β inhibits myogenic differentiation via ID3
por: AlSudais, Hamood, et al.
Publicado: (2018)

CCAAT/Enhancer-Binding Protein Homologous (CHOP) Protein Promotes Carcinogenesis in the DEN-Induced Hepatocellular Carcinoma Model
por: Scaiewicz, Viviana, et al.
Publicado: (2013)

Cyclin D1 overexpression related to retinoblastoma protein expression as a prognostic marker in human oesophageal squamous cell carcinoma.
por: Ishikawa, T., et al.
Publicado: (1998)

Prognostic significance of cyclin E and p53 protein overexpression in carcinoma of the renal pelvis and ureter.
por: Furihata, M., et al.
Publicado: (1998)

High cyclin E1 protein, but not gene amplification, is prognostic for basal‐like breast cancer
por: Aziz, Diar, et al.
Publicado: (2022)

Multiple cullin-associated E3 ligases regulate cyclin D1 protein stability
por: Lu, Ke, et al.
Publicado: (2023)

CCAAT/Enhancer Binding Protein β Regulates Expression of Indian Hedgehog during Chondrocytes Differentiation
por: Ushijima, Takahiro, et al.
Publicado: (2014)

CCAAT-Enhancer Binding Protein-β Expression and Elevation in Alzheimer’s Disease and Microglial Cell Cultures
por: Strohmeyer, Ron, et al.
Publicado: (2014)

Functional Studies of CCAAT/Enhancer Binding Protein Site Located Downstream of the Transcriptional Start Site
por: Liu, Yujie, et al.
Publicado: (2017)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation
por: Wang, Shao-Ming, et al.
Publicado: (2018)

Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts
por: AlSudais, Hamood, et al.
Publicado: (2019)

Anticancer Activity of ST101, A Novel Antagonist of CCAAT/Enhancer Binding Protein β
por: Darvishi, Emad, et al.
Publicado: (2022)

Parallel cyclin E and cyclin A expression in neoplastic lesions of the uterine cervix
por: Erlandsson, F, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_c82pphpq5rpu22ogdahcj9rgk2