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PKCδ-dependent signaling mediates ethambutol-induced toxic effects on human retinal pigment cells

PURPOSE: Our previous report demonstrated that ethambutol (EMB) might induce cytoplasmic vacuolization and reduce the uptake of photoreceptor rod outer segments (ROS) in retinal pigment epithelium (RPE) cells, which are mediated via a protein kinase C (PKC)-dependent pathway. In the present study, w...

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Detalles Bibliográficos
Autores principales:	Tsai, Rong Kung, He, Ming Shan, Chen, Zih-Yao, Wu, Wen Chen, Wu, Wen Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123160/ https://www.ncbi.nlm.nih.gov/pubmed/21738386

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