Cargando…
Determinants of Sensitivity to DZNep Induced Apoptosis in Multiple Myeloma Cells
The 3-Deazaneplanocin A (DZNep), one of S-adenosylhomocysteine (AdoHcy) hydrolase inhibitors, has shown antitumor activities in a broad range of solid tumors and acute myeloid leukemia. Here, we examined its effects on multiple myeloma (MM) cells and found that, at 500 nM, it potently inhibited grow...
Autores principales: | Xie, Zhigang, Bi, Chonglei, Cheong, Lip Lee, Liu, Shaw Cheng, Huang, Gaofeng, Zhou, Jianbiao, Yu, Qiang, Chen, Chien-Shing, Chng, Wee Joo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123372/ https://www.ncbi.nlm.nih.gov/pubmed/21720561 http://dx.doi.org/10.1371/journal.pone.0021583 |
Ejemplares similares
-
Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma
por: Bi, Chonglei, et al.
Publicado: (2015) -
MicroRNA: Important Player in the Pathobiology of Multiple Myeloma
por: Bi, Chonglei, et al.
Publicado: (2014) -
Clonogenic Multiple Myeloma Cells have Shared stemness Signature Associated with Patient Survival
por: Reghunathan, Renji, et al.
Publicado: (2013) -
Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma
por: Xie, Zhigang, et al.
Publicado: (2013) -
The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia
por: Zhou, Jianbiao, et al.
Publicado: (2012)