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Agent-based simulation of reactions in the crowded and structured intracellular environment: Influence of mobility and location of the reactants

BACKGROUND: In this paper we apply a novel agent-based simulation method in order to model intracellular reactions in detail. The simulations are performed within a virtual cytoskeleton enriched with further crowding elements, which allows the analysis of molecular crowding effects on intracellular...

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Detalles Bibliográficos
Autores principales: Klann, Michael T, Lapin, Alexei, Reuss, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123599/
https://www.ncbi.nlm.nih.gov/pubmed/21569565
http://dx.doi.org/10.1186/1752-0509-5-71