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Can localised (19)F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response?

BACKGROUND: 5-Fluorouracil remains widely used in colorectal cancer treatment more than 40 years after its development. 19F magnetic resonance spectroscopy can be used in vivo to measure 5FU’s half-life and metabolism to cytotoxic fluoronucleotides. Previous studies have shown better survival associ...

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Detalles Bibliográficos
Autores principales:	McIntyre, Dominick J. O., Howe, Franklyn A., Ladroue, Christophe, Lofts, Fiona, Stubbs, Marion, Griffiths, John R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123693/ https://www.ncbi.nlm.nih.gov/pubmed/20821329 http://dx.doi.org/10.1007/s00280-010-1438-2

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