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Dysregulation of the Intrarenal Vitamin D Endocytic Pathway in a Nephropathy-Prone Mouse Model of Type 1 Diabetes
Microalbuminuria in humans with Type 1 diabetes (T1D) is associated with increased urinary excretion of megalin, as well as many megalin ligands, including vitamin-D-binding protein (VDBP). We examined the DBA/2J diabetic mouse, nephropathy prone model, to determine if megalin and VDBP excretion coi...
Autores principales: | Fowlkes, John L., Bunn, R. Clay, Cockrell, Gael E., Clark, Lindsey M., Wahl, Elizabeth C., Lumpkin, Charles K., Thrailkill, Kathryn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123992/ https://www.ncbi.nlm.nih.gov/pubmed/21747824 http://dx.doi.org/10.1155/2011/269378 |
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