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Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice

Amphotericin B deoxycholate (AmB), a classic antifungal drug, remains the initial treatment of choice for deep fungal infections, but it is not appropriate for treatment of cryptococcal meningitis due to its inability to pass through the blood–brain barrier (BBB). We examined the efficacy of amphote...

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Detalles Bibliográficos
Autores principales: Xu, Nan, Gu, Julin, Zhu, Yuanjie, Wen, Hai, Ren, Qiushi, Chen, Jianghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124396/
https://www.ncbi.nlm.nih.gov/pubmed/21720503
http://dx.doi.org/10.2147/IJN.S17503