Elucidating the domain architecture and functions of non-core RAG1: The capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding

BACKGROUND: The repertoire of the antigen-binding receptors originates from the rearrangement of immunoglobulin and T-cell receptor genetic loci in a process known as V(D)J recombination. The initial site-specific DNA cleavage steps of this process are catalyzed by the lymphoid specific proteins RAG...

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Detalles Bibliográficos
Autores principales: Arbuckle, Janeen L, Rahman, Negar S, Zhao, Shuying, Rodgers, William, Rodgers, Karla K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124419/
https://www.ncbi.nlm.nih.gov/pubmed/21599978
http://dx.doi.org/10.1186/1471-2091-12-23

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