Circulating Tumor Cells and Cardiac Metastasis from Esophageal Cancer: A Case Report

We report the case of a 67-year-old man affected by metastatic esophageal cancer. The patient developed a symptomatic heart metastasis presenting as mimicking ST-segment elevation myocardial infarction. Cardiac magnetic resonance imaging (MRI) documented the presence of a mass in the apex and septum...

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Detalles Bibliográficos
Autores principales: Consoli, Francesca, Arcangeli, Giuseppina, Ferrari, Vittorio, Grisanti, Salvatore, Almici, Camillo, Bordonali, Tania, Simoncini, Edda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: May 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124464/
https://www.ncbi.nlm.nih.gov/pubmed/21734885
http://dx.doi.org/10.1159/000329021
Descripción
Sumario:We report the case of a 67-year-old man affected by metastatic esophageal cancer. The patient developed a symptomatic heart metastasis presenting as mimicking ST-segment elevation myocardial infarction. Cardiac magnetic resonance imaging (MRI) documented the presence of a mass in the apex and septum of the left ventriculum. The dissemination of cancer was confirmed by the detection of circulating tumor cells (CTCs) in the peripheral blood, measured by the CellSearch System (Veridex, LLC, Raritan, N.J., USA). The blood sample drawn at cardiac disease progression revealed the presence of 2 CTCs per 7.5 ml of blood. This report highlights the potential role of CTCs as markers of metastatic spread.

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