Overexpression of Nrdp1 in the Heart Exacerbates Doxorubicin-Induced Cardiac Dysfunction in Mice

BACKGROUND: Cardiac cell death and generation of oxidative stress contribute to doxorubicin (DOX)-induced cardiac dysfunction. E3 ligase Nrdp1 plays a critical role in the regulation of cell apoptosis, inflammation and production of reactive oxygen species (ROS), which may contribute to heart failur...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yuan, Kang, Yu-Ming, Tian, Cui, Zeng, Yong, Jia, Li-Xin, Ma, Xu, Du, Jie, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124482/
https://www.ncbi.nlm.nih.gov/pubmed/21738612
http://dx.doi.org/10.1371/journal.pone.0021104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124482/
https://www.ncbi.nlm.nih.gov/pubmed/21738612
http://dx.doi.org/10.1371/journal.pone.0021104

Ejemplares similares