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Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells
Polarized molecular activities play important roles in guiding the cell toward persistent and directional migration. In this study, the polarized distributions of the activities of phosphatidylinositol 3-kinase (PI3K) and the Rac1 small GTPase were monitored using chimeric fluorescent proteins (FPs)...
Autores principales: | Lu, Shaoying, Kim, Tae-jin, Chen, Chih-En, Ouyang, Mingxing, Seong, Jihye, Liao, Xiaoling, Wang, Yingxiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124492/ https://www.ncbi.nlm.nih.gov/pubmed/21738630 http://dx.doi.org/10.1371/journal.pone.0021293 |
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