Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in part to its genetic variability, structural heterogeneity and lability. However, the extent of lability in Env function, particularly for primary isolates across clades, has not been explored. Here, we...

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Detalles Bibliográficos
Autores principales: Agrawal, Nitish, Leaman, Daniel P., Rowcliffe, Eric, Kinkead, Heather, Nohria, Raman, Akagi, Junya, Bauer, Katherine, Du, Sean X., Whalen, Robert G., Burton, Dennis R., Zwick, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124497/
https://www.ncbi.nlm.nih.gov/pubmed/21738637
http://dx.doi.org/10.1371/journal.pone.0021339

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