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Characterisation of a Desmosterol Reductase Involved in Phytosterol Dealkylation in the Silkworm, Bombyx mori

Most species of invertebrate animals cannot synthesise sterols de novo and many that feed on plants dealkylate phytosterols (mostly C(29) and C(28)) yielding cholesterol (C(27)). The final step of this dealkylation pathway involves desmosterol reductase (DHCR24)-catalysed reduction of desmosterol to...

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Detalles Bibliográficos
Autores principales: Ciufo, Leonora F., Murray, Patricia A., Thompson, Anu, Rigden, Daniel J., Rees, Huw H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124498/
https://www.ncbi.nlm.nih.gov/pubmed/21738635
http://dx.doi.org/10.1371/journal.pone.0021316