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Normalization in MALDI-TOF imaging datasets of proteins: practical considerations
Normalization is critically important for the proper interpretation of matrix-assisted laser desorption/ionization (MALDI) imaging datasets. The effects of the commonly used normalization techniques based on total ion count (TIC) or vector norm normalization are significant, and they are frequently...
Autores principales: | Deininger, Sören-Oliver, Cornett, Dale S., Paape, Rainer, Becker, Michael, Pineau, Charles, Rauser, Sandra, Walch, Axel, Wolski, Eryk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124646/ https://www.ncbi.nlm.nih.gov/pubmed/21479971 http://dx.doi.org/10.1007/s00216-011-4929-z |
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