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Modeling and phylogeny analysis of bread wheat MnSOD
Superoxide dismutase (SOD) acts as first line of defense against oxidative and genetic stress. Manganese superoxide dismutase (MnSOD), found in mitochondria or peroxisomes, contains Mn(III) at the active site. Therefore, it is of interest to study MnSOD from bread wheat (a grain crop). However, a st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124787/ https://www.ncbi.nlm.nih.gov/pubmed/21738317 |
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author | Sheoran, Sonia Pandey, Bharati Singh, Rajender Sharma, Pradeep Chatrath, Ravish |
author_facet | Sheoran, Sonia Pandey, Bharati Singh, Rajender Sharma, Pradeep Chatrath, Ravish |
author_sort | Sheoran, Sonia |
collection | PubMed |
description | Superoxide dismutase (SOD) acts as first line of defense against oxidative and genetic stress. Manganese superoxide dismutase (MnSOD), found in mitochondria or peroxisomes, contains Mn(III) at the active site. Therefore, it is of interest to study MnSOD from bread wheat (a grain crop). However, a structure model is not yet solved for bread wheat MnSOD. Hence, we describe the structure model of bread wheat MnSOD developed using homology model. The model provides molecular insight to metal binding molecular function towards the understanding of oxidative stress resistance in plants. The distinction of bread wheat (a monocot) MnSOD from dicots is also shown using phylogenetic analysis. |
format | Online Article Text |
id | pubmed-3124787 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-31247872011-07-07 Modeling and phylogeny analysis of bread wheat MnSOD Sheoran, Sonia Pandey, Bharati Singh, Rajender Sharma, Pradeep Chatrath, Ravish Bioinformation Hypothesis Superoxide dismutase (SOD) acts as first line of defense against oxidative and genetic stress. Manganese superoxide dismutase (MnSOD), found in mitochondria or peroxisomes, contains Mn(III) at the active site. Therefore, it is of interest to study MnSOD from bread wheat (a grain crop). However, a structure model is not yet solved for bread wheat MnSOD. Hence, we describe the structure model of bread wheat MnSOD developed using homology model. The model provides molecular insight to metal binding molecular function towards the understanding of oxidative stress resistance in plants. The distinction of bread wheat (a monocot) MnSOD from dicots is also shown using phylogenetic analysis. Biomedical Informatics 2011-06-06 /pmc/articles/PMC3124787/ /pubmed/21738317 Text en © 2011 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Hypothesis Sheoran, Sonia Pandey, Bharati Singh, Rajender Sharma, Pradeep Chatrath, Ravish Modeling and phylogeny analysis of bread wheat MnSOD |
title | Modeling and phylogeny analysis of bread wheat MnSOD |
title_full | Modeling and phylogeny analysis of bread wheat MnSOD |
title_fullStr | Modeling and phylogeny analysis of bread wheat MnSOD |
title_full_unstemmed | Modeling and phylogeny analysis of bread wheat MnSOD |
title_short | Modeling and phylogeny analysis of bread wheat MnSOD |
title_sort | modeling and phylogeny analysis of bread wheat mnsod |
topic | Hypothesis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124787/ https://www.ncbi.nlm.nih.gov/pubmed/21738317 |
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