The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres

The aim of the present study was to prepare valdecoxib, a cyclo-oxygenase-2 enzyme inhibitor, as a loaded multiparticulate system to achieve site-specific drug delivery to colorectal tumors. Film coating was done with the pH-sensitive polymer Eudragit S100 and sodium alginate was used as mucoadhesiv...

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Detalles Bibliográficos
Autores principales: Thakral, Naveen K, Ray, Alok R, Bar-Shalom, Daniel, Eriksson, André Huss, Majumdar, Dipak K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124854/
https://www.ncbi.nlm.nih.gov/pubmed/21720517
http://dx.doi.org/10.2147/IJN.S19561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124854/
https://www.ncbi.nlm.nih.gov/pubmed/21720517
http://dx.doi.org/10.2147/IJN.S19561

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