Cargando…

Arginase and Arginine Dysregulation in Asthma

In recent years, evidence has accumulated indicating that the enzyme arginase, which converts L-arginine into L-ornithine and urea, plays a key role in the pathogenesis of pulmonary disorders such as asthma through dysregulation of L-arginine metabolism and modulation of nitric oxide (NO) homeostasi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Benson, Renée C., Hardy, Karen A., Morris, Claudia R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124954/ https://www.ncbi.nlm.nih.gov/pubmed/21747870 http://dx.doi.org/10.1155/2011/736319

Ejemplares similares

Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma()
por: Bratt, Jennifer M., et al.
Publicado: (2011)

The role and control of arginine levels in arginase 1 deficiency
por: Diaz, George A., et al.
Publicado: (2022)

Arginine and Arginases Modulate Metabolism, Tumor Microenvironment and Prostate Cancer Progression
por: Matos, Andreia, et al.
Publicado: (2021)

Deprivation of arginine by recombinant human arginase in prostate cancer cells
por: Hsueh, Eddy C, et al.
Publicado: (2012)

Asthma in Sickle Cell Disease
por: Newaskar, Manisha, et al.
Publicado: (2011)

Effect of Arginase Inhibition on Pulmonary L-Arginine Metabolism in Murine Pseudomonas Pneumonia
por: Mehl, Anne, et al.
Publicado: (2014)

Local Suppression of T Cell Responses by Arginase-Induced L-Arginine Depletion in Nonhealing Leishmaniasis
por: Modolell, Manuel, et al.
Publicado: (2009)

Arginase-1 Deficiency Regulates Arginine Concentrations and NOS2-Mediated NO Production during Endotoxemia
por: Wijnands, Karolina A. P., et al.
Publicado: (2014)

Correction: Effect of Arginase Inhibition on Pulmonary L-Arginine Metabolism in Murine Pseudomonas Pneumonia
Publicado: (2014)

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
por: Rath, Meera, et al.
Publicado: (2014)

Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase
por: Mordhorst, Silja, et al.
Publicado: (2023)

Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity
por: Wijnands, Karolina A.P., et al.
Publicado: (2015)

An alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme
por: Romagnoli, G, et al.
Publicado: (2014)

Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells
por: Zhou, Bo, et al.
Publicado: (2021)

Association of increased risk of asthma with elevated arginase & interleukin-13 levels in serum & rs2781666 G/T genotype of arginase I
por: Donthi, Suhasini, et al.
Publicado: (2018)

L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis
por: Aoki, Juliana Ide, et al.
Publicado: (2017)

Examining the role of arginase in air pollution-induced exacerbation of asthma
por: North, Michelle L, et al.
Publicado: (2010)

Arginase and pulmonary diseases
por: Maarsingh, Harm, et al.
Publicado: (2008)

Protein arginine methyltransferase 5 (PRMT5) dysregulation in cancer
por: Shailesh, Harshita, et al.
Publicado: (2018)

The Inhibition of Arginase by N (ω)-Hydroxy-l-Arginine Controls the Growth of Leishmania Inside Macrophages
por: Iniesta, Virginia, et al.
Publicado: (2001)

Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease
por: Reyes, Loretta Z., et al.
Publicado: (2023)

Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation
por: Wells, James W., et al.
Publicado: (2013)

Arginase and Arginine Decarboxylase – Where Do the Putative Gate Keepers of Polyamine Synthesis Reside in Rat Brain?
por: Peters, Daniela, et al.
Publicado: (2013)

TIPE2 Negatively Regulates Inflammation by Switching Arginine Metabolism from Nitric Oxide Synthase to Arginase
por: Lou, Yunwei, et al.
Publicado: (2014)

Cloning and disruption of the UeArginase in Ustilago esculenta: evidence for a role of arginine in its dimorphic transition
por: Zhang, Yafen, et al.
Publicado: (2019)

Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma
por: Tate, David J, et al.
Publicado: (2008)

Arginase Activities and Global Arginine Bioavailability in Wild-Type and ApoE-Deficient Mice: Responses to High Fat and High Cholesterol Diets
por: Erdely, Aaron, et al.
Publicado: (2010)

Manipulation of arginase expression modulates abiotic stress tolerance in Arabidopsis: effect on arginine metabolism and ROS accumulation
por: Shi, Haitao, et al.
Publicado: (2013)

The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated‐recombinant arginase I BCT‐100
por: De Santo, Carmela, et al.
Publicado: (2017)

Arginase inhibition by rhaponticin increases L-arginine concentration that contributes to Ca(2+)-dependent eNOS activation
por: Koo, Bon-Hyeock, et al.
Publicado: (2021)

Endothelial arginase II and atherosclerosis
por: Ryoo, Sungwoo, et al.
Publicado: (2011)

Deletion of Genes Encoding Arginase Improves Use of “Heavy” Isotope-Labeled Arginine for Mass Spectrometry in Fission Yeast
por: Borek, Weronika E., et al.
Publicado: (2015)

Recent tPA administration can cause pseudo‐hyperargininemia and may mimic arginase deficiency or arginine supplementation
por: Cusmano‐Ozog, Kristina P., et al.
Publicado: (2022)

Arginine and Nitric Oxide Pathways in Obesity-Associated Asthma
por: Holguin, Fernando
Publicado: (2013)

Arginine metabolic endotypes related to asthma severity
por: Xu, Weiling, et al.
Publicado: (2017)

Immunostimulated enterocytes activate extracellular arginase I which competes with enterocyte inducible nitric oxide synthase for arginine during inflammation
por: Miki, K, et al.
Publicado: (2009)

l-Arginine Supplementation and Metabolism in Asthma
por: Kenyon, Nicholas J., et al.
Publicado: (2011)

The role of the arginine metabolome in pain: implications for sickle cell disease
por: Bakshi, Nitya, et al.
Publicado: (2016)

The arginase inhibitor N(ω)−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
por: Ng, King Pan, et al.
Publicado: (2018)

Treatment with the arginase inhibitor N(w)-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis
por: Prati, Clément, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_39fferl9vimfh2vr9kpbmg68ls