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Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling

Slug, a member of the Snail family of transcription factors, has a crucial role in the regulation of epithelial-mesenchymal transition (EMT) by suppressing several epithelial markers and adhesion molecules, including E-cadherin. A recent study demonstrated that no relationship exists between Slug an...

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Detalles Bibliográficos
Autores principales: Zhang, Kejun, Chen, Dong, Jiao, Xuelong, Zhang, Shaoyan, Liu, Xiangping, Cao, Jingyu, Wu, Liqun, Wang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125102/
https://www.ncbi.nlm.nih.gov/pubmed/21283078
http://dx.doi.org/10.1038/labinvest.2010.201