Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output

The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. Nucleosome number in cells was considered fixed, but recently aging yeast and mammalian cells were shown to contain fewer nucleosomes. We s...

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Detalles Bibliográficos
Autores principales: Celona, Barbara, Weiner, Assaf, Di Felice, Francesca, Mancuso, Francesco M., Cesarini, Elisa, Rossi, Riccardo L., Gregory, Lorna, Baban, Dilair, Rossetti, Grazisa, Grianti, Paolo, Pagani, Massimiliano, Bonaldi, Tiziana, Ragoussis, Jiannis, Friedman, Nir, Camilloni, Giorgio, Bianchi, Marco E., Agresti, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125158/
https://www.ncbi.nlm.nih.gov/pubmed/21738444
http://dx.doi.org/10.1371/journal.pbio.1001086

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