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Subretinal gene delivery using helper-dependent adenoviral vectors

This study describes the successful delivery of helper-dependent adenoviral vectors to the mouse retina with long term and robust levels of reporter expression in the retina without apparent adverse effects. Since these vectors have a large cloning capacity, they have great potential to extend the s...

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Detalles Bibliográficos
Autores principales:	Wu, Linda, Lam, Simon, Cao, Huibi, Guan, Rui, Duan, Rongqi, van der Kooy, Derek, Bremner, Rod, Molday, Robert S, Hu, Jim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125205/ https://www.ncbi.nlm.nih.gov/pubmed/21711866 http://dx.doi.org/10.1186/2045-3701-1-15

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