Cargando…
Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling
Lithium, a drug that has long been used to treat bipolar disorder and some other human pathogenesis, has recently been shown to stimulate neural precursor growth. However, the involved mechanism is not clear. Here, we show that lithium induces proliferation but not survival of neural precursor cells...
Autores principales: | Qu, Zhaoxia, Sun, Dongming, Young, Wise |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125208/ https://www.ncbi.nlm.nih.gov/pubmed/21711903 http://dx.doi.org/10.1186/2045-3701-1-18 |
Ejemplares similares
-
Lithium Chloride Suppresses Colorectal Cancer Cell Survival and Proliferation through ROS/GSK-3β/NF-κB Signaling Pathway
por: Li, Huili, et al.
Publicado: (2014) -
20(S)-protopanaxadiol promotes the migration, proliferation, and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway
por: Lin, Kaili, et al.
Publicado: (2020) -
Lithium and Therapeutic Targeting of GSK-3
por: Snitow, Melinda E., et al.
Publicado: (2021) -
Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation
por: Topol, Lilia, et al.
Publicado: (2003) -
Potential involvement of glycogen synthase kinase (GSK)-3β in a rat model of multiple sclerosis: evidenced by lithium treatment
por: Ahn, Meejung, et al.
Publicado: (2017)