Cargando…
GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness
Kisspeptins (Kp), peptide products of the Kisspeptin-1 (KISS1) gene are endogenous ligands for a G protein-coupled receptor 54 (GPR54). Previous findings have shown that KISS1 acts as a metastasis suppressor in numerous cancers in humans. However, recent studies have demonstrated that an increase in...
Autores principales: | Zajac, Mateusz, Law, Jeffrey, Cvetkovic, Dragana Donna, Pampillo, Macarena, McColl, Lindsay, Pape, Cynthia, Di Guglielmo, Gianni M., Postovit, Lynne M., Babwah, Andy V., Bhattacharya, Moshmi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125256/ https://www.ncbi.nlm.nih.gov/pubmed/21738726 http://dx.doi.org/10.1371/journal.pone.0021599 |
Ejemplares similares
-
GPR54 Regulates ERK1/2 Activity and Hypothalamic Gene Expression in a Gα(q/11) and β-Arrestin-Dependent Manner
por: Szereszewski, Jacob M., et al.
Publicado: (2010) -
Kisspeptin/KISS1R System in Breast Cancer
por: Cvetković, Donna, et al.
Publicado: (2013) -
KISS1/KISS1R in Cancer: Friend or Foe?
por: Guzman, Stephania, et al.
Publicado: (2018) -
The pregnant mouse uterus exhibits a functional kisspeptin/KISS1R signaling system on the day of embryo implantation
por: Fayazi, Mehri, et al.
Publicado: (2015) -
The KiSS-1/GPR54 system: Essential roles in physiological homeostasis and cancer biology
por: Zhu, Nisha, et al.
Publicado: (2020)