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Predicting drug side-effect profiles: a chemical fragment-based approach
BACKGROUND: Drug side-effects, or adverse drug reactions, have become a major public health concern. It is one of the main causes of failure in the process of drug development, and of drug withdrawal once they have reached the market. Therefore, in silico prediction of potential side-effects early i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125260/ https://www.ncbi.nlm.nih.gov/pubmed/21586169 http://dx.doi.org/10.1186/1471-2105-12-169 |