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Predicting drug side-effect profiles: a chemical fragment-based approach

BACKGROUND: Drug side-effects, or adverse drug reactions, have become a major public health concern. It is one of the main causes of failure in the process of drug development, and of drug withdrawal once they have reached the market. Therefore, in silico prediction of potential side-effects early i...

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Detalles Bibliográficos
Autores principales: Pauwels, Edouard, Stoven, Véronique, Yamanishi, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125260/
https://www.ncbi.nlm.nih.gov/pubmed/21586169
http://dx.doi.org/10.1186/1471-2105-12-169