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Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth

BACKGROUND: Homeobox genes murine Rhox5 and human RHOXF1 are expressed in early embryonic stages and then mostly restricted to germline tissues in normal adult, yet they are aberrantly expressed in cancer cells in vitro and in vivo . Here we study the epigenetic regulation and potential functions of...

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Detalles Bibliográficos
Autores principales: Li, Qiang, O'Malley, Mark E, Bartlett, David L, Guo, Z Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125390/
https://www.ncbi.nlm.nih.gov/pubmed/21609483
http://dx.doi.org/10.1186/1476-4598-10-63

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