Differential coupling of visual cortex with default network or frontal-parietal network based on goals

The relationship between top-down enhancement and suppression of sensory cortical activity and large-scale, neural-networks remains unclear. Functional connectivity analysis of human fMRI data revealed visual cortical areas that selectively process relevant information are functionally connected with the frontal-parietal network, while those processing irrelevant information are simultaneously coupled with the default-network. This provides the first evidence that sensory cortical regions are differentially and dynamically coupled with distinct networks based on task goals.