Ribosomal Protein S3: A Multifunctional Target of Attaching/Effacing Bacterial Pathogens

The extraribosomal functions of ribosomal proteins have drawn significant recent attention. Ribosomal protein S3 (RPS3), a component of the eukaryotic 40S ribosomal subunit, is a multifunctional protein that regulates DNA repair, apoptosis, and the innate immune response to bacterial infection. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Xiaofei, Hardwidge, Philip R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125523/
https://www.ncbi.nlm.nih.gov/pubmed/21738525
http://dx.doi.org/10.3389/fmicb.2011.00137
Descripción
Sumario:The extraribosomal functions of ribosomal proteins have drawn significant recent attention. Ribosomal protein S3 (RPS3), a component of the eukaryotic 40S ribosomal subunit, is a multifunctional protein that regulates DNA repair, apoptosis, and the innate immune response to bacterial infection. Here we the review the latest findings about RPS3 extraribosomal functions, with special emphasis on their relation to microbial pathogenesis and enteropathogenic Escherichia coli.

Ejemplares similares