Cargando…

iPath2.0: interactive pathway explorer

iPath2.0 is a web-based tool (http://pathways.embl.de) for the visualization and analysis of cellular pathways. Its primary map summarizes the metabolism in biological systems as annotated to date. Nodes in the map correspond to various chemical compounds and edges represent series of enzymatic reac...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamada, Takuji, Letunic, Ivica, Okuda, Shujiro, Kanehisa, Minoru, Bork, Peer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125749/
https://www.ncbi.nlm.nih.gov/pubmed/21546551
http://dx.doi.org/10.1093/nar/gkr313
_version_ 1782207249556439040
author Yamada, Takuji
Letunic, Ivica
Okuda, Shujiro
Kanehisa, Minoru
Bork, Peer
author_facet Yamada, Takuji
Letunic, Ivica
Okuda, Shujiro
Kanehisa, Minoru
Bork, Peer
author_sort Yamada, Takuji
collection PubMed
description iPath2.0 is a web-based tool (http://pathways.embl.de) for the visualization and analysis of cellular pathways. Its primary map summarizes the metabolism in biological systems as annotated to date. Nodes in the map correspond to various chemical compounds and edges represent series of enzymatic reactions. In two other maps, iPath2.0 provides an overview of secondary metabolite biosynthesis and a hand-picked selection of important regulatory pathways and other functional modules, allowing a more general overview of protein functions in a genome or metagenome. iPath2.0′s main interface is an interactive Flash-based viewer, which allows users to easily navigate and explore the complex pathway maps. In addition to the default pre-computed overview maps, iPath offers several data mapping tools. Users can upload various types of data and completely customize all nodes and edges of iPath2.0′s maps. These customized maps give users an intuitive overview of their own data, guiding the analysis of various genomics and metagenomics projects.
format Online
Article
Text
id pubmed-3125749
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-31257492011-07-05 iPath2.0: interactive pathway explorer Yamada, Takuji Letunic, Ivica Okuda, Shujiro Kanehisa, Minoru Bork, Peer Nucleic Acids Res Articles iPath2.0 is a web-based tool (http://pathways.embl.de) for the visualization and analysis of cellular pathways. Its primary map summarizes the metabolism in biological systems as annotated to date. Nodes in the map correspond to various chemical compounds and edges represent series of enzymatic reactions. In two other maps, iPath2.0 provides an overview of secondary metabolite biosynthesis and a hand-picked selection of important regulatory pathways and other functional modules, allowing a more general overview of protein functions in a genome or metagenome. iPath2.0′s main interface is an interactive Flash-based viewer, which allows users to easily navigate and explore the complex pathway maps. In addition to the default pre-computed overview maps, iPath offers several data mapping tools. Users can upload various types of data and completely customize all nodes and edges of iPath2.0′s maps. These customized maps give users an intuitive overview of their own data, guiding the analysis of various genomics and metagenomics projects. Oxford University Press 2011-07-01 2011-05-05 /pmc/articles/PMC3125749/ /pubmed/21546551 http://dx.doi.org/10.1093/nar/gkr313 Text en © The Author(s) 2011. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Yamada, Takuji
Letunic, Ivica
Okuda, Shujiro
Kanehisa, Minoru
Bork, Peer
iPath2.0: interactive pathway explorer
title iPath2.0: interactive pathway explorer
title_full iPath2.0: interactive pathway explorer
title_fullStr iPath2.0: interactive pathway explorer
title_full_unstemmed iPath2.0: interactive pathway explorer
title_short iPath2.0: interactive pathway explorer
title_sort ipath2.0: interactive pathway explorer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125749/
https://www.ncbi.nlm.nih.gov/pubmed/21546551
http://dx.doi.org/10.1093/nar/gkr313
work_keys_str_mv AT yamadatakuji ipath20interactivepathwayexplorer
AT letunicivica ipath20interactivepathwayexplorer
AT okudashujiro ipath20interactivepathwayexplorer
AT kanehisaminoru ipath20interactivepathwayexplorer
AT borkpeer ipath20interactivepathwayexplorer