Cargando…
NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity
The products of many bacterial non-ribosomal peptide synthetases (NRPS) are highly important secondary metabolites, including vancomycin and other antibiotics. The ability to predict substrate specificity of newly detected NRPS Adenylation (A-) domains by genome sequencing efforts is of great import...
Autores principales: | Röttig, Marc, Medema, Marnix H., Blin, Kai, Weber, Tilmann, Rausch, Christian, Kohlbacher, Oliver |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125756/ https://www.ncbi.nlm.nih.gov/pubmed/21558170 http://dx.doi.org/10.1093/nar/gkr323 |
Ejemplares similares
-
Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)
por: Rausch, Christian, et al.
Publicado: (2005) -
Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
por: Rausch, Christian, et al.
Publicado: (2007) -
Combining Structure and Sequence Information Allows Automated Prediction of Substrate Specificities within Enzyme Families
por: Röttig, Marc, et al.
Publicado: (2010) -
Characterization and Engineering of the Adenylation
Domain of a NRPS-Like Protein: A Potential Biocatalyst for Aldehyde
Generation
por: Wang, Meng, et al.
Publicado: (2014) -
Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters
por: Blin, Kai, et al.
Publicado: (2017)