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DEPTH: a web server to compute depth and predict small-molecule binding cavities in proteins

Depth measures the extent of atom/residue burial within a protein. It correlates with properties such as protein stability, hydrogen exchange rate, protein–protein interaction hot spots, post-translational modification sites and sequence variability. Our server, DEPTH, accurately computes depth and...

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Detalles Bibliográficos
Autores principales: Tan, Kuan Pern, Varadarajan, Raghavan, Madhusudhan, M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125764/
https://www.ncbi.nlm.nih.gov/pubmed/21576233
http://dx.doi.org/10.1093/nar/gkr356