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Detecting selection in immunoglobulin sequences

The ability to detect selection by analyzing mutation patterns in experimentally derived immunoglobulin (Ig) sequences is a critical part of many studies. Such techniques are useful not only for understanding the response to pathogens, but also to determine the role of antigen-driven selection in au...

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Detalles Bibliográficos
Autores principales: Uduman, Mohamed, Yaari, Gur, Hershberg, Uri, Stern, Jacob A., Shlomchik, Mark J., Kleinstein, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125793/
https://www.ncbi.nlm.nih.gov/pubmed/21665923
http://dx.doi.org/10.1093/nar/gkr413