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PILGRM: an interactive data-driven discovery platform for expert biologists

PILGRM (the platform for interactive learning by genomics results mining) puts advanced supervised analysis techniques applied to enormous gene expression compendia into the hands of bench biologists. This flexible system empowers its users to answer diverse biological questions that are often outsi...

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Detalles Bibliográficos
Autores principales: Greene, Casey S., Troyanskaya, Olga G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125802/
https://www.ncbi.nlm.nih.gov/pubmed/21653547
http://dx.doi.org/10.1093/nar/gkr440
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author Greene, Casey S.
Troyanskaya, Olga G.
author_facet Greene, Casey S.
Troyanskaya, Olga G.
author_sort Greene, Casey S.
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description PILGRM (the platform for interactive learning by genomics results mining) puts advanced supervised analysis techniques applied to enormous gene expression compendia into the hands of bench biologists. This flexible system empowers its users to answer diverse biological questions that are often outside of the scope of common databases in a data-driven manner. This capability allows domain experts to quickly and easily generate hypotheses about biological processes, tissues or diseases of interest. Specifically PILGRM helps biologists generate these hypotheses by analyzing the expression levels of known relevant genes in large compendia of microarray data. Because PILGRM is data-driven, it complements a user’s knowledge and literature analysis with mining of diverse functional genomic data, thereby generating novel predictions that can drive experimental follow-up. This server is free, does not require registration and is available for use at http://pilgrm.princeton.edu.
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spelling pubmed-31258022011-07-05 PILGRM: an interactive data-driven discovery platform for expert biologists Greene, Casey S. Troyanskaya, Olga G. Nucleic Acids Res Articles PILGRM (the platform for interactive learning by genomics results mining) puts advanced supervised analysis techniques applied to enormous gene expression compendia into the hands of bench biologists. This flexible system empowers its users to answer diverse biological questions that are often outside of the scope of common databases in a data-driven manner. This capability allows domain experts to quickly and easily generate hypotheses about biological processes, tissues or diseases of interest. Specifically PILGRM helps biologists generate these hypotheses by analyzing the expression levels of known relevant genes in large compendia of microarray data. Because PILGRM is data-driven, it complements a user’s knowledge and literature analysis with mining of diverse functional genomic data, thereby generating novel predictions that can drive experimental follow-up. This server is free, does not require registration and is available for use at http://pilgrm.princeton.edu. Oxford University Press 2011-07-01 2011-06-07 /pmc/articles/PMC3125802/ /pubmed/21653547 http://dx.doi.org/10.1093/nar/gkr440 Text en © The Author(s) 2011. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Greene, Casey S.
Troyanskaya, Olga G.
PILGRM: an interactive data-driven discovery platform for expert biologists
title PILGRM: an interactive data-driven discovery platform for expert biologists
title_full PILGRM: an interactive data-driven discovery platform for expert biologists
title_fullStr PILGRM: an interactive data-driven discovery platform for expert biologists
title_full_unstemmed PILGRM: an interactive data-driven discovery platform for expert biologists
title_short PILGRM: an interactive data-driven discovery platform for expert biologists
title_sort pilgrm: an interactive data-driven discovery platform for expert biologists
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125802/
https://www.ncbi.nlm.nih.gov/pubmed/21653547
http://dx.doi.org/10.1093/nar/gkr440
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