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A Beta-mixture model for dimensionality reduction, sample classification and analysis
BACKGROUND: Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper we propose a beta-mixture model to describe genome-wide methylation patterns based on probe data from methylation microar...
Autores principales: | Laurila, Kirsti, Oster, Bodil, Andersen, Claus L, Lamy, Philippe, Orntoft, Torben, Yli-Harja, Olli, Wiuf, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126746/ https://www.ncbi.nlm.nih.gov/pubmed/21619656 http://dx.doi.org/10.1186/1471-2105-12-215 |
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