Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)

Plantaricin 423, produced by Lactobacillus plantarum, and bacteriocin ST4SA produced by Enterococcus mundtii, were electrospun into nanofibers prepared from different combinations of poly(d,l-lactide) (PDLLA) and poly(ethylene oxide) (PEO) dissolved in N,N-dimethylformamide (DMF). Both peptides were...

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Detalles Bibliográficos
Autores principales: Heunis, Tiaan, Bshena, Osama, Klumperman, Bert, Dicks, Leon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127109/
https://www.ncbi.nlm.nih.gov/pubmed/21731433
http://dx.doi.org/10.3390/ijms12042158
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author Heunis, Tiaan
Bshena, Osama
Klumperman, Bert
Dicks, Leon
author_facet Heunis, Tiaan
Bshena, Osama
Klumperman, Bert
Dicks, Leon
author_sort Heunis, Tiaan
collection PubMed
description Plantaricin 423, produced by Lactobacillus plantarum, and bacteriocin ST4SA produced by Enterococcus mundtii, were electrospun into nanofibers prepared from different combinations of poly(d,l-lactide) (PDLLA) and poly(ethylene oxide) (PEO) dissolved in N,N-dimethylformamide (DMF). Both peptides were released from the nanofibers with a high initial burst and retained 88% of their original antimicrobial activity at 37 °C. Nanofibers have the potential to serve as carrier matrix for bacteriocins and open a new field in developing controlled antimicrobial delivery systems for various applications.
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spelling pubmed-31271092011-06-30 Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO) Heunis, Tiaan Bshena, Osama Klumperman, Bert Dicks, Leon Int J Mol Sci Article Plantaricin 423, produced by Lactobacillus plantarum, and bacteriocin ST4SA produced by Enterococcus mundtii, were electrospun into nanofibers prepared from different combinations of poly(d,l-lactide) (PDLLA) and poly(ethylene oxide) (PEO) dissolved in N,N-dimethylformamide (DMF). Both peptides were released from the nanofibers with a high initial burst and retained 88% of their original antimicrobial activity at 37 °C. Nanofibers have the potential to serve as carrier matrix for bacteriocins and open a new field in developing controlled antimicrobial delivery systems for various applications. Molecular Diversity Preservation International (MDPI) 2011-03-29 /pmc/articles/PMC3127109/ /pubmed/21731433 http://dx.doi.org/10.3390/ijms12042158 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Heunis, Tiaan
Bshena, Osama
Klumperman, Bert
Dicks, Leon
Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
title Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
title_full Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
title_fullStr Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
title_full_unstemmed Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
title_short Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(d,l-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
title_sort release of bacteriocins from nanofibers prepared with combinations of poly(d,l-lactide) (pdlla) and poly(ethylene oxide) (peo)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127109/
https://www.ncbi.nlm.nih.gov/pubmed/21731433
http://dx.doi.org/10.3390/ijms12042158
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