Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy

OBJECTIVE: To study the effect of brimonidine on intraocular pressure (IOP) following capsulotomy among Indian subjects. MATERIALS AND METHODS: The study was a nonrandomized trial with open label. RESULTS: 80% of the subjects showed a decrease in IOP after instilling 0.2% brimonidine (1 hour pre cap...

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Autores principales: Singhal, Deepika, Desai, Roopali, Desai, Sejal, Shastri, Manisha, Saxena, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127336/
https://www.ncbi.nlm.nih.gov/pubmed/21772770
http://dx.doi.org/10.4103/0976-500X.81902
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author Singhal, Deepika
Desai, Roopali
Desai, Sejal
Shastri, Manisha
Saxena, Deepak
author_facet Singhal, Deepika
Desai, Roopali
Desai, Sejal
Shastri, Manisha
Saxena, Deepak
author_sort Singhal, Deepika
collection PubMed
description OBJECTIVE: To study the effect of brimonidine on intraocular pressure (IOP) following capsulotomy among Indian subjects. MATERIALS AND METHODS: The study was a nonrandomized trial with open label. RESULTS: 80% of the subjects showed a decrease in IOP after instilling 0.2% brimonidine (1 hour pre capsulotomy). No such decrease was observed in control. After 1 and 4 h post capsulotomy a statistically significant decrease in IOP ranging between 1–10 mmHg was found in 73.3% of the treatment group. CONCLUSIONS: In the present study 0.2% brimonidine has been proven effective to counteract the increase in IOP following Nd-YAG laser capsulotomy in Indian setting.
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spelling pubmed-31273362011-07-19 Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy Singhal, Deepika Desai, Roopali Desai, Sejal Shastri, Manisha Saxena, Deepak J Pharmacol Pharmacother Research Paper OBJECTIVE: To study the effect of brimonidine on intraocular pressure (IOP) following capsulotomy among Indian subjects. MATERIALS AND METHODS: The study was a nonrandomized trial with open label. RESULTS: 80% of the subjects showed a decrease in IOP after instilling 0.2% brimonidine (1 hour pre capsulotomy). No such decrease was observed in control. After 1 and 4 h post capsulotomy a statistically significant decrease in IOP ranging between 1–10 mmHg was found in 73.3% of the treatment group. CONCLUSIONS: In the present study 0.2% brimonidine has been proven effective to counteract the increase in IOP following Nd-YAG laser capsulotomy in Indian setting. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3127336/ /pubmed/21772770 http://dx.doi.org/10.4103/0976-500X.81902 Text en Copyright: © Journal of Pharmacology and Pharmacotherapeutics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Paper
Singhal, Deepika
Desai, Roopali
Desai, Sejal
Shastri, Manisha
Saxena, Deepak
Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
title Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
title_full Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
title_fullStr Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
title_full_unstemmed Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
title_short Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
title_sort use of topical brimonidine to prevent intraocular pressure elevations following nd: yag-laser posterior capsulotomy
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127336/
https://www.ncbi.nlm.nih.gov/pubmed/21772770
http://dx.doi.org/10.4103/0976-500X.81902
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