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Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive rats

OBJECTIVE: Insulin resistance, diabetes, and hypertension are considered elements of metabolic syndrome which is associated with vascular dysfunction. We investigated whether inhibition of protein kinase C (PKC) would affect vascular function in diabetic hypertensive (DH) rats. METHODS: A combinatio...

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Detalles Bibliográficos
Autores principales:	Lu, Xiao, Bean, James S, Kassab, Ghassan S, Rekhter, Mark D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127756/ https://www.ncbi.nlm.nih.gov/pubmed/21635764 http://dx.doi.org/10.1186/1475-2840-10-48

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