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Mild hypothermia causes differential, time-dependent changes in cytokine expression and gliosis following endothelin-1-induced transient focal cerebral ischemia

BACKGROUND: Stroke is an important cause of morbidity and mortality and few therapies exist thus far. Mild hypothermia (33°C) is a promising neuroprotective strategy to improve outcome after ischemic stroke. However, its complete mechanism of action has not yet been fully elaborated. This study is t...

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Detalles Bibliográficos
Autores principales: Ceulemans, An-Gaëlle, Zgavc, Tine, Kooijman, Ron, Hachimi-Idrissi, Said, Sarre, Sophie, Michotte, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127770/
https://www.ncbi.nlm.nih.gov/pubmed/21627837
http://dx.doi.org/10.1186/1742-2094-8-60