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Expansion of CD4(+)CD25(+ )helper T cells without regulatory function in smoking and COPD

BACKGROUND: Regulatory T cells have been implicated in the pathogenesis of COPD by the increased expression of CD25 on helper T cells along with enhanced intracellular expression of FoxP3 and low/absent CD127 expression on the cell surface. METHOD: Regulatory T cells were investigated in BALF from n...

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Detalles Bibliográficos
Autores principales:	Roos-Engstrand, Ester, Pourazar, Jamshid, Behndig, Annelie F, Bucht, Anders, Blomberg, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127771/ https://www.ncbi.nlm.nih.gov/pubmed/21651772 http://dx.doi.org/10.1186/1465-9921-12-74

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