Hierarchical Cluster-based Partial Least Squares Regression (HC-PLSR) is an efficient tool for metamodelling of nonlinear dynamic models

BACKGROUND: Deterministic dynamic models of complex biological systems contain a large number of parameters and state variables, related through nonlinear differential equations with various types of feedback. A metamodel of such a dynamic model is a statistical approximation model that maps variati...

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Detalles Bibliográficos
Autores principales: Tøndel, Kristin, Indahl, Ulf G, Gjuvsland, Arne B, Vik, Jon Olav, Hunter, Peter, Omholt, Stig W, Martens, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127793/
https://www.ncbi.nlm.nih.gov/pubmed/21627852
http://dx.doi.org/10.1186/1752-0509-5-90

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