Construction and Modelling of an Inducible Positive Feedback Loop Stably Integrated in a Mammalian Cell-Line

Understanding the relationship between topology and dynamics of transcriptional regulatory networks in mammalian cells is essential to elucidate the biology of complex regulatory and signaling pathways. Here, we characterised, via a synthetic biology approach, a transcriptional positive feedback loo...

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Detalles Bibliográficos
Autores principales: Siciliano, Velia, Menolascina, Filippo, Marucci, Lucia, Fracassi, Chiara, Garzilli, Immacolata, Moretti, Maria Nicoletta, di Bernardo, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127819/
https://www.ncbi.nlm.nih.gov/pubmed/21765813
http://dx.doi.org/10.1371/journal.pcbi.1002074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127819/
https://www.ncbi.nlm.nih.gov/pubmed/21765813
http://dx.doi.org/10.1371/journal.pcbi.1002074

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