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Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32)

BACKGROUND: Elevated numbers of regulatory T cells (T(regs)) have been implicated in certain cancers. Depletion of T(regs )has been shown to increase anti-tumor immunity. T(regs )also play a critical role in the suppression of autoimmune responses. The study of T(regs )has been hampered by a lack of...

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Detalles Bibliográficos
Autores principales:	Chan, Derek V, Somani, Ally-Khan, Young, Andrew B, Massari, Jessica V, Ohtola, Jennifer, Sugiyama, Hideaki, Garaczi, Edina, Babineau, Denise, Cooper, Kevin D, McCormick, Thomas S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127830/ https://www.ncbi.nlm.nih.gov/pubmed/21615933 http://dx.doi.org/10.1186/1471-2091-12-27

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