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SMAC Mimetic BV6 Induces Cell Death in Monocytes and Maturation of Monocyte-Derived Dendritic Cells

BACKGROUND: Compounds mimicking the inhibitory effect of SMAC / DIABLO on X-linked inhibitor of apoptosis (XIAP) have been developed with the aim to achieve sensitization for apoptosis of tumor cells resistant due to deregulated XIAP expression. It turned out that SMAC mimetics also have complex eff...

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Detalles Bibliográficos
Autores principales:	Müller-Sienerth, Nicole, Dietz, Lena, Holtz, Philipp, Kapp, Markus, Grigoleit, Götz Ulrich, Schmuck, Carsten, Wajant, Harald, Siegmund, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127953/ https://www.ncbi.nlm.nih.gov/pubmed/21738708 http://dx.doi.org/10.1371/journal.pone.0021556

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