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Pros and cons of a prion-like pathogenesis in Parkinson's disease
BACKGROUND: Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder which affects widespread areas of the brainstem, basal ganglia and cerebral cortex. A number of proteins are known to accumulate in parkinsonian brains including ubiquitin and α-synuclein. Prion diseases are...
Autores principales: | Hilker, Ruediger, Brotchie, Jonathan M, Chapman, Joab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128002/ https://www.ncbi.nlm.nih.gov/pubmed/21689433 http://dx.doi.org/10.1186/1471-2377-11-74 |
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