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A novel and well-defined benchmarking method for second generation read mapping
BACKGROUND: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almost identical or highly similar reference genome. The assessment of the quality of read mapping results is not straightfor...
Autores principales: | Holtgrewe, Manuel, Emde, Anne-Katrin, Weese, David, Reinert, Knut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128034/ https://www.ncbi.nlm.nih.gov/pubmed/21615913 http://dx.doi.org/10.1186/1471-2105-12-210 |
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