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Epithelial to Mesenchymal Transition by TGFβ-1 Induction Increases Stemness Characteristics in Primary Non Small Cell Lung Cancer Cell Line
BACKGROUND: Cancer Stem Cells (CSCs) hypothesis asserts that only a small subset of cells within a tumour is capable of both tumour initiation and sustainment. The Epithelial-Mesenchymal Transition (EMT) is an embryonic developmental program that is often activated during cancer invasion and metasta...
Autores principales: | Pirozzi, Giuseppe, Tirino, Virginia, Camerlingo, Rosa, Franco, Renato, La Rocca, Aantonello, Liguori, Eleonora, Martucci, Nicola, Paino, Francesca, Normanno, Nicola, Rocco, Gaetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128060/ https://www.ncbi.nlm.nih.gov/pubmed/21738704 http://dx.doi.org/10.1371/journal.pone.0021548 |
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