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Association Pattern of Interleukin-1 Receptor-Associated Kinase-4 Gene Polymorphisms with Allergic Rhinitis in a Han Chinese Population

OBJECTIVE: Interleukin-1 receptor-associated kinase-4 (IRAK-4) encodes a kinase that is essential for NF-kB activation in Toll-like receptor and T-cell receptor signaling pathways, indicating a possible crosstalk between innate and acquired immunities. We attempted to determine whether the polymorph...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Lin, Xiaoping, Desrosiers, Martin, Zhang, Wei, Meng, Na, Zhao, Liping, Han, Demin, Zhang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128076/
https://www.ncbi.nlm.nih.gov/pubmed/21738793
http://dx.doi.org/10.1371/journal.pone.0021769