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Broad Antiviral Activity of Carbohydrate-Binding Agents against the Four Serotypes of Dengue Virus in Monocyte-Derived Dendritic Cells
BACKGROUND: Dendritic cells (DC), present in the skin, are the first target cells of dengue virus (DENV). Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) is present on DC and recognizes N-glycosylation sites on the E-glycoprotein of DENV. Thus, the DC-SIGN/E...
Autores principales: | Alen, Marijke M. F., De Burghgraeve, Tine, Kaptein, Suzanne J. F., Balzarini, Jan, Neyts, Johan, Schols, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128091/ https://www.ncbi.nlm.nih.gov/pubmed/21738755 http://dx.doi.org/10.1371/journal.pone.0021658 |
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