Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals

Sudden cardiac death (SCD) continues to be one of the leading causes of mortality worldwide, with an annual incidence estimated at 250,000–300,000 in the United States and with the vast majority occurring in the setting of coronary disease. We performed a genome-wide association meta-analysis in 1,2...

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Autores principales: Arking, Dan E., Junttila, M. Juhani, Goyette, Philippe, Huertas-Vazquez, Adriana, Eijgelsheim, Mark, Blom, Marieke T., Newton-Cheh, Christopher, Reinier, Kyndaron, Teodorescu, Carmen, Uy-Evanado, Audrey, Carter-Monroe, Naima, Kaikkonen, Kari S., Kortelainen, Marja-Leena, Boucher, Gabrielle, Lagacé, Caroline, Moes, Anna, Zhao, XiaoQing, Kolodgie, Frank, Rivadeneira, Fernando, Hofman, Albert, Witteman, Jacqueline C. M., Uitterlinden, André G., Marsman, Roos F., Pazoki, Raha, Bardai, Abdennasser, Koster, Rudolph W., Dehghan, Abbas, Hwang, Shih-Jen, Bhatnagar, Pallav, Post, Wendy, Hilton, Gina, Prineas, Ronald J., Li, Man, Köttgen, Anna, Ehret, Georg, Boerwinkle, Eric, Coresh, Josef, Kao, W. H. Linda, Psaty, Bruce M., Tomaselli, Gordon F., Sotoodehnia, Nona, Siscovick, David S., Burke, Greg L., Marbán, Eduardo, Spooner, Peter M., Cupples, L. Adrienne, Jui, Jonathan, Gunson, Karen, Kesäniemi, Y. Antero, Wilde, Arthur A. M., Tardif, Jean-Claude, O'Donnell, Christopher J., Bezzina, Connie R., Virmani, Renu, Stricker, Bruno H. C. h., Tan, Hanno L., Albert, Christine M., Chakravarti, Aravinda, Rioux, John D., Huikuri, Heikki V., Chugh, Sumeet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128111/
https://www.ncbi.nlm.nih.gov/pubmed/21738491
http://dx.doi.org/10.1371/journal.pgen.1002158

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