A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a strong genetic predisposition, characterized by an upregulated type I interferon pathway. MicroRNAs are important regulators of immune homeostasis, and aberrant microRNA expression has been demonstrated in patients with autoim...

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Detalles Bibliográficos
Autores principales: Luo, Xiaobing, Yang, Wanling, Ye, Dong-Qing, Cui, Huijuan, Zhang, Yan, Hirankarn, Nattiya, Qian, Xiaoxia, Tang, Yuanjia, Lau, Yu Lung, de Vries, Niek, Tak, Paul Peter, Tsao, Betty P., Shen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128113/
https://www.ncbi.nlm.nih.gov/pubmed/21738483
http://dx.doi.org/10.1371/journal.pgen.1002128

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