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A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus
Neutralizing antibodies are a significant component of the host's protective response against flavivirus infection. Neutralization of flaviviruses occurs when individual virions are engaged by antibodies with a stoichiometry that exceeds a required threshold. From this “multiple-hit” perspectiv...
Autores principales: | Dowd, Kimberly A., Jost, Christiane A., Durbin, Anna P., Whitehead, Stephen S., Pierson, Theodore C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128118/ https://www.ncbi.nlm.nih.gov/pubmed/21738473 http://dx.doi.org/10.1371/journal.ppat.1002111 |
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